Walther-Straub-Institut für Pharmakologie und Toxikologie
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Publikationen

Veröffentlichungen

PubMed

Veröffentlichungen seit 2015

Originalveröffentlichungen

  • Weber, J., Rajan, S., Schremmer, C., Chao, Y.K., Krasteva-Christ, G., Kannler, M., Yildirim, A.Ö., Brosien, M., Schredelseker, J., Weissmann, N., Grimm, C., Gudermann, T., Dietrich, A. (2020). TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema. JCI Insight 5:e134464. doi: 10.1172/jci.insight.134464.
  • Murtaza, B., Hichami, A., Khan, A.S., Plesnik, J., Sery, O., Dietrich, A., Birnbaumer, L,. Khan, N.A. (2020). Implication of TRPC3 channel in gustatory perception of dietary lipids. Acta Physiol 3:e13554. doi: 10.1111/apha.13554.
  • Lüling, R., Schmeißer, W., Siegert, M., Mückter, H., Dietrich, A., Thiermann, H., Gudermann, T., John, H., Steinritz, D. (2020). Identification of creatine kinase and alpha-1 antitrypsin as protein targets of alkylation by sulfur mustard.
    Drug Test Anal doi: 10.1002/dta.2916.
  • Camacho Londoño, J.E., Kuryshev, V., Zorn, M., Saar, K., Tian, Q., Hübner, N., Nawroth, P., Dietrich, A., Birnbaumer, L., Lipp, P., Dieterich, C., Freichel, M. (2020). Transcriptional Signatures regulated by TRPC1/C4-mediated background Ca2+ entry after pressure-overload induced cardiac remodelling. Prog Biophys Mol Biol doi: 10/1016/jpbiomolbio.2020.07.006.
  • Tsvilovskyy, V., Solis-Lopez, A., Almering, J., Richter, C., Birnbaumer, L., Dietrich, A., Freichel M. (2020). Analysis of Mrgprb2 Receptor-Evoked Ca2+ Signaling in Bone Marrow Derived (BMMC) and Peritoneal (PMC) Mast Cells of TRPC-Deficient Mice. Front Immunol 8: 564. doi: 10.3389/fimmu.2020.00564.
  • Kepura, F., Braun, E., Dietrich, A., Plant, T.D. (2020). TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons. Cells 9: 459. doi: 10.3390/cells9020459
  • Bendiks, L., Geiger, F., Gudermann, T., Feske, S., Dietrich, A. (2020). Store-operated Ca2+ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration. Sci Rep 10: 6812. doi: 10.1038/s41598-020-63677-2.
  • Camacho Londoño, J.E., Marx, A., Kraft, A.E., Schürger, A., Richter, C., Dietrich, A., Lipp, P., Birn-baumer, L., Freichel, M. (2020). Angiotensin-II-Evoked Ca2+ Entry in Murine Cardiac Fibroblasts Does Not Depend on TRPC Channels. Cells 9: E322.
  • Fiedler, S., Storch, U., Erdogmus, S., Gudermann, T., Mederos Y Schnitzler, M., Dietrich, A. (2019). Small Fluorescein Arsenical Hairpin-Based Förster Resonance Energy Transfer Analysis Reveals Changes in Amino- to Carboxyl-Terminal Interactions upon OAG Activation of Classical Transient Receptor Potential 6. Mol Pharm 96: 90-98. doi: 10.1124/mol.119.115949.
  • Strielkov, I., Krause, N.C., Sommer, N., Schermuly, R.T., Ghofrani, H.A., Grimminger, F., Gudermann, T., Dietrich, A., Weissmann, N. (2018). Hypoxic pulmonary vasoconstriction in isolated mouse pul-monary arterial vessels. Exp Physiol 103: 1185-1191.
  • Kannler, M., Lüling, R., Yildirim, A.Ö., Gudermann, T., Steinritz, D., Dietrich, A. (2018). TRPA1 channels: expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia. Pflügers Arch 470: 1231-1241.
  • Häfner, S., Burg, F., Kannler, M., Urban, N., Mayer, P., Dietrich, A., Trauner, D., Broichhagen, J., Schaefer. M. (2018). A (+)-Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6. ChemMedChem. 13:1028-1035. doi: 10.1002/cmdc.201800021.
  • Bröker-Lai, J., Kollewe, A., Schindeldecker, B., Pohle, J., Nguyen Chi, V., Mathar, I., Guzman, R., Schwarz, Y., Lai, A., Weißgerber, P., Schwegler, H., Dietrich, A., Both, M., Sprengel, R., Draguhn, A., Köhr, G., Fakler, B., Flockerzi, V., Bruns, D., Freichel, M. (2017). Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J 36: 2770-2789.
  • Hofmann, K., Fiedler, S., Vierkotten, S., Weber, J., Klee, S., Jia, J., Zwickenpflug, W., Flockerzi, V., Storch, U., Yildirim, A.Ö., Gudermann, T., Königshoff, M., Dietrich, A. (2017). Classical transient receptor potential (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis. Biochem Biophys Acta 1863: 560-568.
  • Andersen, K., Kesper, M.S., Marschner, J.A., Konrad, L., Ryu, M., Kumar, Vr. S., Kulkarni, O.P., Mu-lay, S.R., Romoli, S., Demleitner, J., Schiller, P., Dietrich, A., Müller, S., Gross, O., Ruscheweyh, H.J., Huson, D.H., Stecher, B., Anders, H.J. (2017). Intestinal dysbiosis, barrier dysfunction and bac-terial translocation account for CKD-related systemic inflammation. J of Am Soc Nephrol 28: 76-83.
  • Tomar, D., Dong, Z., Shanmughapriya, S., Koch, D.A., Thomas, T., Hoffmann, N.E., Timbala, S.A.; Goldman, S.J., Breves, S.L., Corbally, D.P., Nemani, N., Fairweather, J.P., Cutri, A.R., Zhang, X., Song, J., Jana, F., Huang, J., Barrero, C., Rabinowitz, J.E., Luongo, T.S., Schumacher, S.M., Rock-man, M.E., Dietrich, A., Merali, S., Caplan, J., Stathopulos, P., Ahima, R.S., Cheung, J.Y., Houser, S.R., Koch, W.J., Patel, V., Gohli, V.M., Elrod, J.W., Rajan, S., Madesh, M. (2016). MCUR1 is a scaf-fold factor for the MCU complex function and promotes mitochondrial bioenergetics. Cell Rep 15: 1673-1685.
  • Forst, A.-L., Olteanu, V.S., Mollet, G., Wlodowski, T., Schaefer, F., Dietrich, A., Reiser, J., Guder-mann, T., Mederos y Schnitzler, M., Storch, U. (2016). Purinergic P2X4 channels are crucial mecha-notransducers in podocytes mediating disorganization of the cytoskeleton. J of Am Soc Nephrol 27: 848-662.
  • Camacho Londoño, J.E.; Tian, Q.; Hammer, K., Camacho Londoño, J.; Rei, J., Oberhofer, M.; Mannebach, S.; Mathar, I., Philipp, S., Tabellion, W., Schweda, F., Dietrich, A., Kästner, L., Laufs, U., Birnbaumer, L., Flockerzi, V., Freichel, M., Lipp P. (2015). A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of cardiac hypertrophy. Eur Heart J 36: 2257-2266.
  • Kalwa, M., Storch, U., Demleitner, J., Fiedler, S., Mayer, T., Kannler, M., Fahlbusch, M., Barth, H., Smrcka, A., Hildebrandt, F., Gudermann, T. and Dietrich, A., (2015). Phospholipase C epsilon-induced TRPC6 activation: A common but redundant mechanism in primary podocytes. J Cell Physiol 230:1389-1399.
  • Domes, K., Patrucco, E., Loga, F., Dietrich, A., Birnbaumer, L., Wegener, J.W., Hofmann, F. (2015). Murine cardiac growth, TRPC channels, and cGMP kinase I. Pflügers Arch 467: 2229 -2234,
  • Griesi-Oliveira, K., Acab, A., Gupta, A.R., Sunaga, DY., Chailangkarn, T., Nicol, X., Nunez, Y., Walker, M.F., Murdoch, J.D., Sanders, S.J., Fernandez, T.V., Ji, W., Lifton, R.P., Vadasz, E., Dietrich, A., Pradhan, D., Song, H., Ming, G-l, Guoe, X., Haddad, G., Marchetto, M.C.N., Spitzer, N., Passos-Bueno, M.R., State, M.W., Muotri, A.R. (2015). Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry 20: 1350- 1365

Übersichtsartikel, Editorial, Buchbeiträge

  • Käsmann, L., Dietrich, A., Staab-Weijnitz, C.A., Manapov, F., Behr, J., Rimner, A., Jeremic, B., Senan, S., De Ruysscher, D., Lauber, K., Belka. C. (2020). Radiation-induced lung toxicity - cellular and molecular mechanisms of pathogenesis, management, and literature review. Radiat Oncol 15: 214. doi: 10.1186/s13014-020-01654-9.
  • Dietrich, A. (2019). Transient Receptor Potential (TRP) Channels in Health and Disease (2019). Cells 8: E413
  • Dietrich, A. (2019) Modulators of Transient Receptor Potential (TRP) Channels as Therapeutic Options in Lung Disease. Pharmaceuticals 12:23. doi: 10.3390/ph12010023.
  • Steinritz, D., Stenger, B., Dietrich, A., Gudermann, T., Popp, T. (2018) TRPs in Tox: Involvement of Transient Receptor Potential-Channels in Chemical-Induced Organ Toxicity-A Structured Review. Cells 7: E98 doi: 10.3390/cells7080098.
  • Dietrich, A., Steinritz, D., Gudermann, T. (2017). Transient receptor potential (TRP) channels as molecular targets in lung toxicology and associated diseases. Cell Calcium 67: 123-137. doi: 10.1016/j.ceca.2017.04.005.
  • Pak, O., Sydykov, A., Kosanovic, D., Schermuly, R.T., Dietrich, A., Schröder, K., Brandes, R.P., Gu-dermann, T., Sommer, N., Weissmann, N. (2017). Lung Ischaemia-Reperfusion Injury: The Role of Reactive Oxygen Species. Adv Exp Med Biol 967: 195-225.
  • Malczyk, M., Erb, A., Veith, C., Ghofrani, H.A., Schermuly, R.T., Gudermann, T., Dietrich, A., Weiss-mann, N., Sydykov, A. (2017). The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature. Front Immunol 8: 707.
  • Malczyk, M., Veith, C., Schermuly, R.T., Gudermann, T., Dietrich, A., Sommer, N., Weissmann, N., Pak, O. (2015). NADPH oxidases – do they play a role in TRPC regulation under hypoxia? Pflügers Arch 468: 23-41.